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Add:5th Floor, Building 9, Nanjing Life Science and Technology Innovation Town, No. 568 Longmian Avenue, Jiangning District, Nanjing, Jiangsu, China
Phone:025-83326929
Fax:025-83326929

 

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Study on substitution of pharmacological toxicants

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Pharmacological evaluation is an important part of innovative drug research, including preliminary pharmacodynamic studies, preliminary pharmacokinetic studies and preliminary safety evaluation. The results of the drug-based evaluation can provide the efficacy and safety data of the drug at an early stage of drug development, and it is a preliminary study to determine whether the compound has the potential to develop into a drug. The key to its work lies in the reliability of the test data and the efficiency of the test. . The company has experienced researchers in the field of drug-based evaluation. The testers have many years of experience in pharmacology and toxicology research, and have many years of experience in large-scale domestic safety assessment agencies. The analysis department has a number of advanced equipment such as imported high-performance liquid chromatography, gas chromatograph, ultraviolet spectrophotometer, etc., which can formulate a drug evaluation test program for innovative drugs including traditional Chinese medicine, chemical medicine and biological medicine. Accurately and quickly provide preliminary pharmacodynamics, pharmacokinetics and safety data to provide a reliable basis for decision making.

The work we can carry out:

1. Preliminary pharmacodynamic studies: including pharmacodynamic tests at the cellular level, in vivo and ex vivo organs, and animal levels;

2. Pharmacokinetic studies: including pharmacokinetic tests in mice, rats, dogs, etc. under non-GLP conditions;

3. Preliminary safety evaluation: including acute toxicity test in mice, rats and dogs under non-GLP conditions, three-way test (carcinogenic, teratogenic, mutagenic) and local irritation test.