Add：5th Floor, Building 9, Nanjing Life Science and Technology Innovation Town, No. 568 Longmian Avenue, Jiangning District, Nanjing, Jiangsu, China
Study on substitution of pharmacological toxicants
Pharmacological evaluation is an important part of innovative drug research, including preliminary pharmacodynamic studies, preliminary pharmacokinetic studies and preliminary safety evaluation. The results of the drug-based evaluation can provide the efficacy and safety data of the drug at an early stage of drug development, and it is a preliminary study to determine whether the compound has the potential to develop into a drug. The key to its work lies in the reliability of the test data and the efficiency of the test. . The company has experienced researchers in the field of drug-based evaluation. The testers have many years of experience in pharmacology and toxicology research, and have many years of experience in large-scale domestic safety assessment agencies. The analysis department has a number of advanced equipment such as imported high-performance liquid chromatography, gas chromatograph, ultraviolet spectrophotometer, etc., which can formulate a drug evaluation test program for innovative drugs including traditional Chinese medicine, chemical medicine and biological medicine. Accurately and quickly provide preliminary pharmacodynamics, pharmacokinetics and safety data to provide a reliable basis for decision making.
The work we can carry out:
1. Preliminary pharmacodynamic studies: including pharmacodynamic tests at the cellular level, in vivo and ex vivo organs, and animal levels;
2. Pharmacokinetic studies: including pharmacokinetic tests in mice, rats, dogs, etc. under non-GLP conditions;
3. Preliminary safety evaluation: including acute toxicity test in mice, rats and dogs under non-GLP conditions, three-way test (carcinogenic, teratogenic, mutagenic) and local irritation test.