Druggability evaluation is an important part of innovative drug research, including preliminary pharmacodynamic studies, preliminary pharmacokinetic studies and preliminary safety evaluation. The results of druggability evaluation can provide efficacy and safety data of the drug at an early stage of drug development. It is a preliminary research work to determine whether a compound has the potential to be developed into a drug. The key to this work lies in the reliability of test data and test efficiency. . The company has experienced professional researchers for druggability evaluation. The testers all have many years of experience in pharmacology and toxicology research, and have many years of experience working in large domestic safety evaluation institutions. The analysis department is equipped with multiple imported high-performance liquid chromatographs, gas chromatographs, UV spectrophotometers and other advanced equipment. It can formulate targeted drug evaluation test plans for innovative drugs including traditional Chinese medicines, chemical drugs, and biological drugs. Accurately and quickly provide preliminary pharmacodynamics, pharmacokinetics and safety data of drugs to provide reliable basis for decision-making.
The research the company can currently carry out includes:
1. Preliminary pharmacodynamic research: including pharmacodynamic tests at the cell level, in vivo and in vitro organ levels, and animal levels;
2. Pharmacokinetic research: including pharmacokinetic tests on mice, rats, dogs, etc. under non-GLP conditions;
3. Preliminary safety evaluation: including acute toxicity tests on mice, rats, and dogs, three-cause tests (carcinogenicity, teratogenicity, mutagenicity), and local irritation tests under non-GLP conditions.